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Research Paper on Pharmacogenetics
The research paper evaluates the effects of gene mutation on the drug metabolism. We comprehensively assessed the drug metabolizing capabilities of CYP2C19 variants using two substrates, S-mephenytoin and omeprazole and used the PyMOL software for molecular visualization.
Seo, M. E., Min, B. J., Heo, N., Lee, K. H., & Kim, J. H. (2023). Comprehensive in vitro and in silico assessments of metabolic capabilities of 24 genomic variants of CYP2C19 using two different substrates. Frontiers in pharmacology, 14, 1055991. https://doi.org/10.3389/fphar.2023. 1055991
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